He died at his home with his family by his bedside, a family spokesman said.
Mushonga, a former deputy mayor of Harare, was married to Regional Integration and International Cooperation Minister Priscilla Misihairabwi-Mushonga.
While the minister was out of the country, a heavily armed gang raided her Mt Pleasant home after disarming a police officer guarding the property before brutally assaulting her husband, a maid and a family friend.
Dr Mushonga, said to have been repeatedly struck on the head with the butt of an AK47 rifle in an apparent robbery, sustained serious head injuries and severe internal bleeding.
Dr Mushonga recently had a lumbar puncture performed to correct bleeding around the brain which had paralysed his spinal cord. That operation left him unable to talk and fighting for his life, a family spokesman said.
Seven men have been arrested and charged with attempted murder for the attack on Mushonga, maid Maria Mandizha and the minister’s UK-based friend Michelle Hakata. Those charges could now be altered to include murder.
The seven are Makaika Milanzi, 33, Assan Chikwada, 29, Tichaona Soda, 31, Crispen Sibanda, 50, Antony Khumbula, 31, Steven Zvinoseva, 26, and Tendai Jongwe, 38.
The minister was too distraught to talk on Sunday.